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Learner Reviews & Feedback for Epigenetic Control of Gene Expression by The University of Melbourne

4.8
stars
820 ratings

About the Course

While the human genome sequence has transformed our understanding of human biology, it isn’t just the sequence of your DNA that matters, but also how you use it! How are some genes activated and others are silenced? How is this controlled? The answer is epigenetics. Epigenetics has been a hot topic for research over the past decade as it has become clear that aberrant epigenetic control contributes to disease (particularly to cancer). Epigenetic alterations are heritable through cell division, and in some instances are able to behave similarly to mutations in terms of their stability. Importantly, unlike genetic mutations, epigenetic modifications are reversible and therefore have the potential to be manipulated therapeutically. It has also become clear in recent years that epigenetic modifications are sensitive to the environment (for example diet), which has sparked a large amount of public debate and research. This course will give an introduction to the fundamentals of epigenetic control. We will examine epigenetic phenomena that are manifestations of epigenetic control in several organisms, with a focus on mammals. We will examine the interplay between epigenetic control and the environment and finally the role of aberrant epigenetic control in disease. All necessary information will be covered in the lectures, and recommended and required readings will be provided. There are no additional required texts for this course. For those interested, additional information can be obtained in the following textbook. Epigenetics. Allis, Jenuwein, Reinberg and Caparros. Cold Spring Harbour Laboratory Press. ISBN-13: 978-0879697242 | Edition: 1 The course will re-open in 2022....

Top reviews

NN

Aug 2, 2021

T​his is the best course on coursera, 10/10. I wish it was longer and I could take it all over again. you will need background knowledge for this course but it is an amazing course and I will miss it.

MM

Oct 2, 2018

This was an excellent course. All the material was well presented and the explanation of the sometimes complex subject matter was clear and understandable. Thank you for an great learning experience.

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176 - 200 of 226 Reviews for Epigenetic Control of Gene Expression

By Karoline B R P

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Dec 7, 2020

That course was so incredible!

By Mirtha M C O

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Jun 10, 2016

excellent course in all sense!

By Alaa W

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Sep 29, 2024

exciting and simple course

By Mary S

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Sep 21, 2024

Excelente é muito didático

By Puja M

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May 14, 2020

This course was so good.

By Nandini K

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May 16, 2020

very informative course

By Amália L

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Aug 18, 2016

This course is amazing!

By Alfredo C

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May 19, 2020

thanks for evriyhing

By Durga s .

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Nov 1, 2021

Highly motivating .

By Afolake A

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Mar 19, 2019

A very good course.

By Pedro T

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Oct 10, 2016

It's pretty good :)

By Carolina A

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Nov 27, 2023

Useful and amazing

By Bart S

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Mar 27, 2016

very comprehensive

By Erika R

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May 13, 2020

Excellent course.

By Paul R

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Nov 25, 2019

Excellent course!

By Andrés H O

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Jun 12, 2018

Very nice course!

By Gloria J

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Oct 8, 2018

Excellent course

By Dimas D T S C

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Jun 6, 2016

just amazing =D

By Philip B P J

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Apr 22, 2016

Very well done.

By Alejandra E P

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Sep 30, 2024

excelente curo

By Elias F

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Jun 20, 2024

It's very good

By penguins0r0bol

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May 17, 2020

Fascinating!

By kumaresan T

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Sep 20, 2019

Nice course!

By Dinesh K R M

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May 18, 2020

Excellent!

By Mayookha M

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Nov 28, 2020

Excellent